https://ebsina.or.id/journals/index.php/jkki/issue/feed Jurnal Kesehatan Komunitas Indonesia 2026-05-15T16:11:32+00:00 Fahruddin Kurdi, S.Kep., Ns., M.Kep. Fahruddinkurdi@gmail.com Open Journal Systems <p style="text-align: justify;"><span lang="EN-US"><strong>Journal of Indonesian Community Health (Jurnal Kesehatan Komunitas Indonesia)/ JKKI</strong> is an open access scientific journal managed electronically by EBSINA and published by Al-Hijrah Indonesia. JKKI focuses on the areas of public health and care, epidemiology, pharmacy, reproductive health, health management, environmental health, health promotion, occupational safety, community nutrition, health policy, and others related to health in the community, clinical, and industrial setting. Indonesian Journal of Community Health (JKKI) published in <strong>April, August, and December. </strong></span></p> <p style="text-align: justify;"><span lang="EN-US">Jurnal Kesehatan Komunitas Indonesia has been accredited as <a href="https://sinta.kemdiktisaintek.go.id/journals/profile/15866" target="_blank" rel="noopener"><strong>SINTA-3</strong> </a>by Ministry of Higher Education, Science and Technology Republic of Indonesia.</span></p> https://ebsina.or.id/journals/index.php/jkki/article/view/682 The Relationship Between Mental Health Literacy and The Attitude Toward Seeking Professional Psychological Help in Junior High School 2026-04-22T16:01:16+00:00 Rhifa Sasqi Nurazijah rhifanrz15@gmail.com Sifa Fauziah sifafauziah317@gmail.com Papat Patimah papatpatimah225@gmail.com <p>Adolescent mental health is an important aspect of individual development. However, a limited understanding of mental health causes adolescents to have difficulty recognizing psychological issues, which tends to result in attitudes that are less supportive when seeking professional help. This study aims to analyze the relationship between mental health literacy and attitudes toward seeking professional psychological help among adolescents at Bersemi Integrated Islamic Junior High School. This study used a quantitative approach with a cross- sectional design. The research sample consisted of 83 respondents selected through purposive sampling. Data collection was conducted <span style="font-size: 0.875rem;">using the Mental Health Literacy Questionnaire (MHLQ) and Attitudes Toward Seeking Professional Psychological Help (ATSPPH) questionnaires. Data analysis was carried out univariately and bivariately using the Chi-Square test. The results shows that the majority of respondents have a moderate level of mental health literacy (56.6%) and a positive attitude toward seeking professional psychological help (57.8%). The bivariate analysis results show a p-value of 0.020, indicating a meaningful relationship between mental health literacy and attitudes toward seeking professional psychological help.There is a significant relationship between mental health literacy and the attitude toward seeking professional psychological help among adolescents. The higher the level of mental health literacy, the more positive the attitude in seeking professional psychological help.</span></p> 2026-04-21T00:00:00+00:00 Copyright (c) 2026 Rhifa Sasqi Nurazijah, Sifa Fauziah, Papat Patimah https://ebsina.or.id/journals/index.php/jkki/article/view/685 Community Health Workers’ Digital Competencies in Using Digital Technologies and Artificial Intelligence 2026-04-22T16:01:13+00:00 Sabrina Intan Zoraya sabrinazoraya@unizar.ac.id Abdillah Adipatria Budi Azhar abdillahadipatria@unizar.ac.id Winda Kurnia Sari sabrinazoraya@unizar.ac.id Iman Saladin Budi Azhar sabrinazoraya@unizar.ac.id Rizma Adlia Syakurah sabrinazoraya@unizar.ac.id <p><strong>Background:</strong> Strengthening community health workers’ (CHWs) digital competencies is critical to ensuring that digital health transformation translates into improved community-level services. <strong>Aims:</strong> This systematic review aimed to synthesize evidence on the effectiveness of training, empowerment, or capacity-building interventions in enhancing CHWs’ competencies in using digital technologies and artificial intelligence (AI). <strong>Methods:</strong> Following PRISMA guidelines, articles published between 2016 and 2026 were identified from four databases. Quantitative studies and community-based implementation reports assessing improvements in digital knowledge and/or skills were included. <strong>Results:</strong> Of 885 records screened, 30 met eligibility criteria. Interventions encompassed mobile health applications, web-based information systems, digital data management tools, and AI-assisted screening platforms. Most studies reported significant gains in knowledge scores, digital data entry and reporting skills, electronic form management, digital surveillance, and AI-assisted interpretation. Improvements in data completeness, timeliness, and perceived reporting accuracy were also documented. However, sustainability challenges emerged, including limited internet infrastructure, unequal access to devices, heterogeneous baseline digital literacy, reliance on external mentoring, short-term evaluations, and incomplete integration with routine health information systems. <strong>Conclusion:</strong> Overall, structured digital training interventions consistently enhance CHWs’ competencies and support the strengthening of primary health care. Sustainable impact, however, requires institutional embedding, standardized tiered training, infrastructure investment, and governance mechanisms to prevent digital initiatives from remaining fragmented pilot projects.</p> 2026-04-22T00:00:00+00:00 Copyright (c) 2026 Sabrina Intan Zoraya, Abdillah Adipatria Budi Azhar, Winda Kurnia Sari, Iman Saladin Budi Azhar, Rizma Adlia Syakurah https://ebsina.or.id/journals/index.php/jkki/article/view/679 The Relationship Between Digital Information Exposure and Social Stigma in People with Mental Disorders in Rural Areas Based on Traditional Culture 2026-04-22T16:01:15+00:00 Stefani Chairunisa Kurniawati stevanichr22@gmail.com Sifa Fauziah sifafauziah317@gmail.com Sri Kurnia Dewi srikurniadewi2017@gmail.com <p><strong>Background:</strong> Social stigma toward people with mental disorders (PMD/ODGJ) remains prevalent in rural communities, where traditional cultural beliefs often reinforce negative perceptions. Limited exposure to evidence-based digital health information may exacerbate stigma by hindering accurate mental health literacy. <strong>Objective:</strong> This study aimed to examine the relationship between digital information exposure and social stigma toward PMD in a traditional rural setting. <strong>Methods:</strong> A quantitative cross-sectional study was conducted in Nyalindung Village, Cianjur Regency, involving 109 community members selected via purposive sampling. Digital information exposure was measured using the eHealth Literacy Scale (eHEALS), and social stigma was assessed using the Perceived Devaluation and Discrimination Scale (PDDS). Data were analyzed using descriptive statistics and the Chi-Square test (α = 0.05). <strong>Results:</strong> The majority of respondents reported low digital information exposure (52.3%), and 78.9% exhibited high social stigma toward PMD. Statistical analysis revealed a significant relationship between digital information exposure and social stigma (p &lt; 0.001), with lower exposure strongly associated with higher stigma levels. <strong>Conclusion:</strong> Limited exposure to digital mental health information is significantly associated with elevated social stigma in traditional rural communities. Integrating culturally sensitive, digital-based mental health literacy interventions into primary healthcare and community outreach programs is recommended to reduce stigma and foster inclusive support systems.</p> 2026-04-22T00:00:00+00:00 Copyright (c) 2026 Stefani Chairunisa Kurniawati, Sifa Fauziah, Sri Kurnia Dewi https://ebsina.or.id/journals/index.php/jkki/article/view/686 The Relationship between Self-Care Needs and Hypertension Control as a Means of Preventing Medical Emergencies in Patients with Chronic Kidney Disease 2026-04-28T12:56:43+00:00 Aneu Rahmawati aneurahmawati47@gmail.com Shinta Arini Ayu shinta.ariniay@gmail.com Obar barik.hamda@gmail.com <p><strong>Background:</strong> Chronic kidney disease is often accompanied by hypertension and carries a risk of medical emergencies. Blood pressure control can be achieved through self-care practices, particularly dietary salt reduction. <strong>Objective:</strong> This study aims to determine the relationship between self-care requisites and blood pressure control in patients with chronic kidney disease. <strong>Methods:</strong> This cross-sectional study involved 109 respondents selected through accidental sampling. Data were collected using the Dietary Salt Reduction Self-Care Behavior (DSR-SCB) questionnaire and blood pressure measurements, then analyzed using the Chi-square test. <strong>Results:</strong> Most respondents had adequate self-care (45.0%), while 52.3% had uncontrolled blood pressure. The Chi-square test showed a significant association between self-care level and blood pressure control (p &lt; 0.001), with better self-care correlating with improved blood pressure control. <strong>Conclusion:</strong> There is a significant association between self-care practices and blood pressure control among patients with chronic kidney disease. Enhanced patient education on self-care, particularly salt restriction, is essential to prevent complications.</p> 2026-04-24T00:00:00+00:00 Copyright (c) 2026 Aneu Rahmawati, Shinta Arini Ayu, Obar https://ebsina.or.id/journals/index.php/jkki/article/view/695 The Role of Family in Pain Management among Patients with Chronic Illness 2026-04-28T12:56:42+00:00 Amita Audilla audillaamita10@gmail.com Farida poprimf@gmail.com Nurhidayati nnurhidayati966@gmail.com Surtini surtini@stikestulungagung.ac.id Suharyoto Suharyoto@stikestulungagung.ac.id <p>Chronic diseases are major health problems often accompanied by persistent pain that can reduce patients’ quality of life. Pain management is not only dependent on medical therapy but is also influenced by the role of the family as the primary support system. The purpose of this study was to determine the relationship between family role and pain management among patients with chronic illness. This study used a quantitative, cross-sectional design. The sample consisted of 35 respondents selected using total sampling in Boyolangu Village, Tulungagung Regency. Data were collected using a family role questionnaire, and pain level was measured using the Numeric Rating Scale (NRS). The study was conducted in January 2026. Data analysis was performed using univariate and bivariate analysis with the Spearman Rank test. The results showed that most respondents had a good family role (57.1%). The majority of respondents (48.6%) experienced moderate pain. Bivariate analysis indicated a significant relationship between family role and pain level (p = 0.002; p &lt; 0.05). The correlation coefficient (r = -0.45) showed a moderate negative relationship, meaning that better family role was associated with lower pain levels. In conclusion, there is a significant relationship between family role and pain management among patients with chronic illness; therefore, healthcare providers are encouraged to enhance family involvement in pain management to improve patients’ quality of life.</p> 2026-04-28T00:00:00+00:00 Copyright (c) 2026 Amita Audilla, Farida, Nurhidayati, Surtini, Suharyoto https://ebsina.or.id/journals/index.php/jkki/article/view/600 Domino and Leaflet Media: Efforts to Improve Adolescents’ Knowledge about Premarital Sex 2026-05-06T02:27:49+00:00 Kustin kustinhariyono@gmail.com Ico Bayu Dewangkoro kustinhariyono@gmail.com <p>Several issues faced by adolescents today include a lack of knowledge about sexual health, with most adolescents still unaware of the dangers of premarital sex, which can lead to unwanted pregnancies. The aim of this study was to determine the effect of the domino game media on adolescents’ knowledge regarding premarital sex. This study employed a quantitative approach using a quasi-experimental method with a two-group pretest and posttest design. The sampling technique used was non-probability sampling with a purposive sampling approach. The total sample consisted of 64 respondents, divided into 32 participants in the control group and 32 in the intervention group, who were given the domino game at SMK 4 Pancasila Ambulu. Data were analyzed univariately using the Wilcoxon test and bivariately using the Mann–Whitney test with SPSS software. The Wilcoxon test results showed significant differences between the pretest and posttest in both the intervention and control groups, with a p-value of 0.001 (&lt;0.05). Similarly, the Mann–Whitney test also indicated a significant result with a p-value of 0.001 (&lt;0.05). Therefore, it can be concluded that the use of the domino game as an educational medium significantly influenced adolescents’ knowledge about premarital sex. The domino game proved to be a useful learning tool, as the findings showed a marked improvement in adolescents’ knowledge after the intervention compared to before.</p> 2026-04-28T00:00:00+00:00 Copyright (c) 2026 Kustin, Ico Bayu Dewangkoro https://ebsina.or.id/journals/index.php/jkki/article/view/377 Non-Pharmacological Management of Hypertension in the Elderly: Integrating Warm Water Foot Soaks with Slow Deep Breathing Therapy 2026-05-06T02:27:47+00:00 Yasmin Hendita inas.hendita@gmail.com Fahruddin Kurdi fahruddin.fkep@unej.ac.id Iswanto iswanto.karso.1981@gmail.com Maya Firiasari maiafitriasari@gmail.com <p><strong>Background:</strong> Blood pressure tends to increase with age due to elevated peripheral vascular resistance and reduced blood vessel elasticity. Non-pharmacological therapies offer viable alternatives or complement to pharmacological interventions for hypertension management. <strong>Objective:</strong> This study aimed to evaluate the effect of integrating warm-water foot soaks with slow, deep breathing therapy on blood pressure reduction in elderly individuals with hypertension. <strong>Methods:</strong> A case study with a pretest-posttest design was conducted at Bondowoso Nursing Home. The participant was an elderly individual aged &gt;60 years with stage 2 hypertension. Blood pressure was measured using a sphygmomanometer before and after the intervention. The combined intervention consisted of warm-water foot soaks (30-40°C) and slow, deep breathing exercises (4-4-4 technique: 4 seconds inhalation, 4 seconds breath-holding, 4 seconds exhalation) for 15 minutes per session. The intervention was administered twice weekly for two weeks (4 sessions total). <strong>Results:</strong> The mean blood pressure before the intervention was 175.00/92.50 mmHg, which decreased to 169.75/90.75 mmHg after the intervention. The mean reduction in systolic and diastolic blood pressure was 5.25 mmHg and 1.75 mmHg, respectively. <strong>Conclusion:</strong> The integration of warm-water foot soaks and slow, deep breathing therapy shows potential to lower blood pressure among elderly individuals with hypertension. For optimal therapeutic effects, consistent, regular implementation beyond 4 sessions is recommended. This combined non-pharmacological approach can be considered as a complementary therapy in hypertension management for the elderly.</p> 2026-04-29T00:00:00+00:00 Copyright (c) 2026 Yasmin Hendita, Fahruddin Kurdi, Iswanto, Maya Firiasari https://ebsina.or.id/journals/index.php/jkki/article/view/701 Mental Health and Cognitive Outcomes in Older Adults After Disasters: Epidemiological Evidence, Determinants, Interventions, and Tiered Service Models for Policy and Education 2026-05-06T02:27:40+00:00 Iswanto iswanto198@yahoo.co.id Asri asri.um@um-surabaya.ac.id Ratna Puji Priyanti ns.ratnapuji.spj@gmail.com Fahruddin Kurdi fahruddin.fkep@unej.ac.id Maya Fitriasari maiafitriasari@gmail.com <p><strong>Background:</strong> Natural and human-made disasters disproportionately increase the risk of mental health disorders and cognitive decline among older adults through trauma exposure, displacement, social isolation, and disrupted health services. Despite expanding literature, a synthesized evidence base linking epidemiology, determinants, interventions, and scalable service models for policy and educational use remains limited. <strong>Objective:</strong> This study aims to synthesize epidemiological evidence, identify key determinants, map effective interventions, and develop policy-ready tiered service models to support mental health and cognitive recovery in older adults following disasters. <strong>Methods:</strong> This narrative review, enhanced by evidence mapping, employs a bio-psychosocial framework aligned with the Inter-Agency Standing Committee (IASC) tiered MHPSS pyramid. Literature was retrieved from scientific databases (PubMed, Scopus, Web of Science), international clinical and policy guidelines (WHO, IASC, NICE, VA/DoD), and Indonesian context-specific sources. Data were narratively synthesized across epidemiological trends, risk/protective factors, intervention efficacy, and service pathway implementation. <strong>Results:</strong> Post-disaster epidemiological burden varies widely; meta-analyses of older earthquake survivors report pooled prevalences of 19.3% for PTSD, 23.5% for depression, and 10.9% for anxiety. Indonesian evidence (North Lombok) indicates 59.9% PTSD prevalence, strongly associated with chronic comorbidities (OR 2.49). Prospective Japanese cohorts demonstrate that severe housing damage accelerates cognitive decline, an effect moderated by social connectivity. Effective interventions include Psychological First Aid (PFA), task-sharing models (e.g., PM+), trauma-focused psychotherapy, cautious pharmacotherapy, and telehealth adaptations. Implementation requires age-friendly, tiered pathways with standardized screening and referral protocols. <strong>Conclusion:</strong> Post-disaster responses must integrate geriatric-sensitive, tiered MHPSS frameworks that ensure continuity of chronic care, preserve social networks, and establish clear, age-disaggregated monitoring systems. These findings provide a structured evidence base for emergency health policy, community response planning, and public health curriculum development.</p> 2026-04-29T00:00:00+00:00 Copyright (c) 2026 Iswanto Iswanto, Asri, Ratna Puji Priyanti, Fahruddin, Maya Fitriasari https://ebsina.or.id/journals/index.php/jkki/article/view/629 The Effect of Pineapple (Ananas comosus L.) Juice Therapy on Reducing Uric Acid and Pain in the Elderly in Jatiroto Village 2026-05-06T02:27:42+00:00 Umi Latifah umilatifah300303@gmail.com Zainal Abidin zainalabidi@unej.ac.id Widya Addiarto addiartow@gmail.com <p><strong>Background:</strong> Gout arthritis is a prevalent degenerative joint disease among the elderly, characterized by hyperuricemia and joint pain due to monosodium urate crystal deposition. In Indonesia, its prevalence reaches 11.9%, highlighting the need for accessible, non-pharmacological interventions. Pineapple <em>(Ananas comosus L.)</em> contains bromelain and vitamin C, which exhibit anti-inflammatory and uricosuric properties. <strong>Objective:</strong> This study aimed to evaluate the effect of pineapple juice therapy on pain reduction and uric acid levels in elderly patients with gout arthritis. <strong>Methods:</strong> A quasi-experimental one-group pretest–posttest design was employed. Thirty elderly gout patients in Kotokan Hamlet, Jatiroto Village, were selected using a total sampling method. The intervention consisted of 200 mL of fresh pineapple juice consumed daily for seven days. Pain intensity was measured using the Numeric Rating Scale (NRS), and serum uric acid levels were assessed with a portable uric acid meter. Data were analyzed using the Wilcoxon signed-rank test (α = 0.05). <strong>Results:</strong> Post-intervention, pain levels decreased significantly, with 73% of respondents reporting mild pain and 27% reporting no pain. Uric acid levels also shifted significantly from 100% hyperuricemic at baseline to 33% within normal limits and 67% below normal post-intervention (p = 0.000). <strong>Conclusion:</strong> Pineapple juice therapy effectively reduces both pain intensity and uric acid levels in elderly individuals with gout arthritis. It is recommended as a safe, cost-effective, and complementary non-pharmacological therapy for community-based gout management.</p> 2026-04-29T00:00:00+00:00 Copyright (c) 2026 Umi Latifah, Zainal Abidin, Widya Addiarto https://ebsina.or.id/journals/index.php/jkki/article/view/696 The Effect of the QR Code Quartet Card Game on Knowledge of Fruit and Vegetable Consumption Among Adolescents 2026-05-06T22:41:13+00:00 Herlina Amia ade_febryanti@poltekkesbengkulu.ac.id Dino Sumaryono arybarm@gmail.com Ade Febryanti ade_febryanti@poltekkesbengkulu.ac.id <p><strong>Background:</strong> Low consumption of fruits and vegetables among adolescents is a major concern, as it may negatively affect health and increase the risk of non-communicable diseases. Adolescents have high nutritional needs to support growth, development, and learning activities, yet many still adopt unhealthy eating habits. Engaging, technology-based educational efforts are needed to improve adolescents' knowledge about the importance of fruit and vegetable intake. <strong>Objective:</strong> To examine the effect of the QR Code quartet card game on adolescents’ knowledge of fruit and vegetable consumption at Iqra Integrated Islamic Junior High School (SMP IT Iqra), Bengkulu City. <strong>Methods:</strong> This study employed a pre-experimental one-group pretest-posttest design. A total of 33 seventh-grade students were selected using simple random sampling. The instrument used was a validated and reliable knowledge questionnaire. The intervention was carried out through a quartet card game equipped with QR Codes containing educational information on fruits and vegetables. <strong>Results:</strong> The intervention led to a significant increase in students’ knowledge. The QR Code quartet card game proved effective as an interactive learning medium that enhanced students’ understanding of the importance of fruit and vegetable consumption, while also providing an enjoyable learning experience aligned with adolescents’ familiarity with technology. <strong>Conclusion:</strong> The QR Code quartet card game can serve as an innovative and practical medium for nutrition education, applicable in schools and communities.</p> 2026-04-29T00:00:00+00:00 Copyright (c) 2026 Herlina Amia, Dino Sumaryono, Ade Febryanti https://ebsina.or.id/journals/index.php/jkki/article/view/710 The Relationship Between Knowledge Level and Thermoluminescence Dosimetry (TLD) Use Behavior Among Radiographers in a Clinical Setting 2026-05-07T07:30:07+00:00 Delfi Iskardyani delfi.iskardyani@gmail.com Muhammad Sofyan muhammadsofyan542@gmail.com <p>The increasing use of ionizing radiation in medical imaging requires proper monitoring to ensure the safety of radiographers, particularly through the use of Thermoluminescent Dosimeters (TLD). However, inconsistencies in knowledge and behavior regarding TLD usage may affect radiation protection practices. This study aims to determine the relationship between knowledge level and radiographers' behavior regarding the use of TLD. This research used a quantitative analytic design with a cross-sectional approach, involving 28 respondents at the clinical practice sites of the Diploma in Radiography at Adisutjipto Yogyakarta Indonesian Air Force Health Polytechnic. Data were collected using a structured questionnaire consisting of knowledge and behavior variables. The sampling technique used was convenience sampling, and data were analyzed using univariate and bivariate analysis with the Chi-square test. The results showed that the majority of respondents had good knowledge (64.3%) and good behavior (64.3%). A statistically significant relationship was found between knowledge and behavior (p &lt; 0.05). These findings indicate that higher knowledge levels are associated with better compliance in TLD usage, although some inconsistencies remain in technical and procedural aspects. In conclusion, improving knowledge can positively influence behavior; therefore, continuous training, supervision, and reinforcement of radiation safety practices are recommended to enhance compliance in TLD usage.</p> 2026-04-29T00:00:00+00:00 Copyright (c) 2026 Delfi Iskardyani, Muhammad Sofyan https://ebsina.or.id/journals/index.php/jkki/article/view/712 Epidermal Growth Factor Receptor Expression and Mutations as Diagnostic and Predictive Biomarkers in Lung Cancer: A Literature Review 2026-05-07T23:42:57+00:00 Sri Melati Munir melpulmo@yahoo.com Wirsma Arief Harahap wirsma66@gmail.com Masrul Basyar basyarmasrul@gmail.com Noza Hilbertina nozahilbertina@gmail.com <p>Lung cancer remains a leading cause of cancer-related mortality worldwide, with diagnostic challenges due to nonspecific symptoms and limitations in tissue sampling. Molecular biomarkers, particularly Epidermal Growth Factor Receptor (EGFR), have gained attention for improving diagnostic accuracy and understanding tumor biology. EGFR plays a critical role in regulating cell proliferation, differentiation, and survival through multiple signaling pathways. This study aims to analyze the role of EGFR expression as a diagnostic biomarker in lung cancer by reviewing its biological function, molecular mechanisms, and clinical relevance. This study used a literature review approach by collecting relevant articles from databases such as PubMed, Scopus, and Google Scholar. Keywords including “EGFR,” “lung cancer,” and “biomarker” were used to identify studies discussing EGFR expression and its diagnostic value. EGFR overexpression and mutations are frequently found in lung cancer, especially non-small cell lung cancer. Activation of EGFR triggers signaling pathways such as MAPK, PI3K, and STAT, promoting tumor proliferation and survival. Detection methods, including immunohistochemistry, PCR, and FISH, are widely used. EGFR expression has shown potential as a diagnostic biomarker and provides important information for targeted therapy. EGFR expression plays a significant role in lung cancer diagnosis and offers potential as a diagnostic biomarker. However, variations across populations and tumor subtypes require careful interpretation in clinical applications.</p> 2026-04-30T00:00:00+00:00 Copyright (c) 2026 Sri Melati Munir, Wirsma Arief Harahap, Masrul Basyar, Noza Hilbertina https://ebsina.or.id/journals/index.php/jkki/article/view/713 The Effect of Anesthesia on TGF-β Levels in Lung Tumor Patients Undergoing Bronchoscopy: A Literature Review 2026-05-08T12:20:06+00:00 Johannas johannasjoe@yahoo.com Efrida efrida@med.unand.ac.id Masrul Basyar basyarmasrul@gmail.com Eryati Darwin eryatidarwin@med.unand.ac.id <p>Lung cancer remains the leading cause of cancer-related mortality worldwide, with persistently low survival rates. Bronchoscopy is an essential diagnostic procedure in patients with lung tumors and often requires anesthesia to improve comfort and procedural success. Emerging evidence suggests that anesthetic agents and techniques may influence tumor biology through modulation of immune responses and inflammatory mediators. Transforming Growth Factor-Beta (TGF-β) is a multifunctional cytokine involved in cell proliferation, differentiation, immune regulation, and extracellular matrix remodeling, and plays a critical role in cancer progression. This literature review aims to evaluate current evidence regarding the effects of anesthetic agents and techniques on TGF-β levels and their implications for tumor biology in patients with lung tumors undergoing bronchoscopy. A narrative literature review approach was used to analyze scientific publications exploring the relationship between anesthesia, immune modulation, cytokine alterations, and cancer progression, particularly focusing on inhalational and intravenous anesthetics. Surgical stress and anesthetic exposure can alter immune responses through activation of neuroendocrine pathways, leading to cytokine imbalance and immunosuppression. TGF-β exhibits dual roles in cancer, acting as a tumor suppressor in early stages and a tumor promoter in advanced stages. Inhalational anesthetics may enhance tumor progression, whereas intravenous anesthetics such as propofol may have immunomodulatory effects. Anesthetic techniques may influence tumor-related pathways, including TGF-β; however, evidence remains limited and inconsistent, requiring further well-designed studies.</p> 2026-04-30T00:00:00+00:00 Copyright (c) 2026 Johannas, Efrida, Masrul Basyar, Eryati Darwin https://ebsina.or.id/journals/index.php/jkki/article/view/720 Acute Triglyceride Response to 60-Minute Jogging Exercise Among Community-Dwelling Adults in Ternate 2026-05-15T16:11:32+00:00 Fahmi Rizal farizihsan89@gmail.com Nikma nikma2184@gmail.com Viona Deswitha Khondowa vionades53@gmail.com <p><strong>Background:</strong> Elevated triglyceride levels are a recognized modifiable risk factor for cardiovascular disease. While moderate-intensity aerobic exercise is recommended for lipid management, evidence on acute triglyceride responses following 60-Minute jogging session remains limited in Indonesian community settings. <strong>Objective:</strong> This study aimed to analyze acute changes in blood triglyceride levels following 60-Minute jogging session among community members in Ternate City, Indonesia. <strong>Methods:</strong> A quantitative pretest–posttest observational design was employed with 50 participants selected via purposive sampling. Triglyceride concentrations were measured using Point-of-Care Testing (POCT) on capillary blood immediately before and after a standardized 60-minute jogging session. Data were analyzed using descriptive statistics and the Wilcoxon Signed-Rank test. <strong>Results:</strong> Following exercise, the proportion of participants with normal triglyceride levels (&lt;150 mg/dL) increased from 56.0% to 70.0%. The high and very high categories decreased, with the latter reaching 0%. The Wilcoxon Signed-Rank test confirmed a statistically significant reduction in triglyceride levels (Z = −3.421, p &lt; .001) with a large effect size (r = 0.48). <strong>Conclusion:</strong> A single 60-minute jogging session induces a significant acute improvement in triglyceride profiles. These findings support moderate aerobic activity as an effective, accessible non-pharmacological strategy for cardiovascular risk reduction in community health settings.</p> 2026-04-29T00:00:00+00:00 Copyright (c) 2026 Fahmi Rizal, Nikma Nikma, Viona Deswitha Khondowa